The microbial basis of inflammatory bowel diseases
نویسندگان
چکیده
منابع مشابه
The microbial basis of inflammatory bowel diseases
The inflammatory bowel diseases (IBD) are a group of chronic diseases that result from a confluence of genetic and environmental triggers. IBD have two main clinical phenotypes, ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterized by mucosal inflammation that is limited to the colon, beginning in the rectum and extending proximally in a continuous and circumferential fashion. C...
متن کاملThe microbial basis of inflammatory bowel diseases.
Inflammatory bowel diseases (IBD) are chronic, progressive diseases characterized by aberrant immune responses to environmental and gut microbial triggers in genetically susceptible hosts. Clinical, genetic, and experimental data support the role of gut microbes in causing and sustaining these diseases. Our understanding of IBD has changed dramatically as the result of advances in cultivation-i...
متن کاملThe Bowel Microbiota and Inflammatory Bowel Diseases
The human bowel contains a large and biodiverse bacterial community known as the microbiota or microbiome. It seems likely that the microbiota, fractions of the microbiota, or specific species comprising the microbiota provide the antigenic fuel that drives the chronic immune inflammation of the bowel mucosa that is characteristic of Crohn's disease and ulcerative colitis. At least twenty years...
متن کامل[Inflammatory bowel diseases]
OBJECTIVE: To present a review about inflammatory bowel diseases in childhood so that pediatricians become familiar with two diseases (ulcerative colitis and Crohn s disease) that are increasing in incidence. METHODS: Articles of specific gastroenterological journals were analyzed. Information was also obtained from the author s extensive professional experience in the area. RESULTS: The two di...
متن کاملInflammatory bowel diseases.
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2014
ISSN: 0021-9738
DOI: 10.1172/jci72330